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KMID : 0363320010220020251
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Journal of Korean Oriental Internal Medicine
2001 Volume.22 No. 2 p.251 ~ p.256
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One Case Report of Acute Cholestatic-Hepatitis(Drug Induced Hepatitis) After Taking Herbal-Medicine
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Yang Jae-Hoon
Lee Ji-Yeon
Kim Kwan-Sik
Jeong Yong-Jun
Kim Hyung-Kuen
Lee Eon-Jeong
Choi Woo-Jung
Han Sang-Chil
Oh Moung-Jin
Oh Ro-Sa
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Abstract
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In western medicine, there are some reports about herbal medicine induced hepatitis, but in oriental medicine, there are few reports about that.
We experienced one case of drug acute cholestatic-hepatitis in the treatment of oriental medicine for HNP. We treated the patient with acupuncture, physical therapy and herb medicine. The patient’s symptoms improved after two weeks of treatment. In the course of treatment, the patient intermittently complained of general weakness, nausea, yellowish urin, dyspepsia, and abdominal discomfort. We recognized that total bilirubin(7.2mg/dl), direct bilirubin(5.5mg/dl), serum transaminase(AST 360U/L, ALT 354U/L), alkaline phosphatase(16.6 K/A), urobilinogen(++) and bilirubin(++) were elevated. We diagnosed drug induced hepatitis. We stopped giving herb medicine and began giving Saeng gan gunbi-tang and Injin-oryung-san. Saeng gan gunbi-tang and Injin-oryung-san have been used to treat hepatic disease and have been known to have beneficial effects. After 3weeks on medication, the clinical symptoms and liver function improved.
So, we report this case to bring more attention to the safety and toxicity of herbal medicine.
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KEYWORD
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drug induced hepatitis, herbal medicine
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